PRUNINDIHYDROCHALCONE

For Research Use Only.
Category
Chalcones
Cat.No.
NP0949
CAS
4192-90-9
Product Name
PRUNINDIHYDROCHALCONE
Structure

Product Details

Description
Trilobatin, coming from the herbs of Lithocarpus pachyphyllus, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway. It increased superoxide dismutase (SOD) activity. Besides, Trilobatin is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect.
Synonyms
Prunindihydrochalcone; 1-[4-(β-D-Glucopyranosyloxy)-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; Phloretin 4'-glucoside; p-Phloridzin; Trilobatin
IUPAC Name
1-[2,6-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
Molecular Weight
436.4
Molecular Formula
C21H24O10
Canonical SMILES
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)OC3C(C(C(C(O3)CO)O)O)O)O)O
InChI
InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-12-7-14(25)17(15(26)8-12)13(24)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-23,25-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1
InChIKey
GSTCPEBQYSOEHV-QNDFHXLGSA-N
Boiling Point
787.9±60.0 °C at 760 mmHg
Melting Point
163 °C
Flash Point
277.1±26.4 °C
Purity
>98%
Density
1.6±0.1 g/cm3
Solubility
In vitro:
10 mM in DMSO
Appearance
Powder
Application
Anti-inflammatory
Storage
4°C, protect from light
* In solvent :
-80°C, 6 months
-20°C, 1 month (protect from light)
Form
Powder
HS Code
29329990
pKa
6.85±0.40(Predicted)
Vapor Pressure
0.0±2.9 mmHg at 25°C
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