Propafenone hydrochloride

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3438

CAS

34183-22-7

Product Name

Propafenone hydrochloride

Structure

Description

Propafenone is a Class 1C antiarrhythmic as sodium channel blocker by slowing the influx of sodium ions into the cardiac muscle cells.

Synonyms

1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone;
2-(2'-Hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone

IUPAC Name

1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride

Molecular Weight

377.91

Molecular Formula

C21H27NO3·HCl

Canonical SMILES

CCCNCC(O)COC1=CC=CC=C1C(=O)CCC1=CC=CC=C1

InChI

1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3

InChIKey

InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N

Melting Point

171-173°C

Purity

≥98%

Solubility

Soluble in DMSO

Appearance

Off-White Solid

Application

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.

Shelf Life

As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

Storage

Store at RT.

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