Description
Prasugrel is a thienopyridine prodrug that is converted by esterases to a receptor antagonist for purinergic P2Y12 receptors. The blockade of P2Y12 receptor activation prevents platelet aggregation. Prasugrel is metabolized by the liver- and intestinal-dominant carboxylesterases CE1 and CE2 to give a mixture of four enantiomers that inhibit platelet aggregation.
Synonyms
Effient; CS 747; LY640315; CS747; LY 640315; CS-747; LY-640315;
IUPAC Name
[5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
Molecular Formula
C20H20FNO3S
Canonical SMILES
CC(=O)OC1=CC2=C(S1)CCN(C2)C(C3=CC=CC=C3F)C(=O)C4CC4
InChI
InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3
InChIKey
DTGLZDAWLRGWQN-UHFFFAOYSA-N
Appearance
White or off-white power