Pramipexole dihydrochloride

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For Research Use Only.

Category

Impurities

Cat.No.

NP3258

CAS

104632-25-9

Product Name

Pramipexole dihydrochloride

Structure

Product Details

Description

The HCl salt form of pramipexole, a thiazole derivative, is an agonist of dopamine receptor D2, D3 and D4, especially used as D2-receptor agonist which is one of the most classical targets in the treatment of Parkinson's disease. Ki: 3.9, 2.2, 0.5, and 5.

Synonyms

(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine dihydrochloride; Pramipexole Dihydrochloride; Mirapex ER; Pramipexole hydrochloride; SND919; Mirapex; SUD 919CL2Y; SUD919CL2Y; U-98528E; Sifrol; SND 919; KNS-760704; SND-919; KNS 760704; KNS760704

IUPAC Name

(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;dihydrochloride

Molecular Weight

284.25

Molecular Formula

C10H17N3S·2(HCl)

Canonical SMILES

CCCNC1CCC2=C(C1)SC(=N2)N.Cl.Cl

InChI

1S/C10H17N3S.2ClH/c1-2-4-10(12)5-3-7-8(6-10)14-9(11)13-7;;/h2-6,12H2,1H3,(H2,11,13);2*1H/t10-;;/m0../s1

InChIKey

OVFMIJINNIJYKB-XRIOVQLTSA-N

Purity

98%

Solubility

Water >20 mg/mL DMSO >80 mg/mL

Appearance

Solid powder

Application

The HCl salt form of pramipexole is an agonist of dopamine receptor D2, D3 and D4, especially used as D2-receptor agonist.

Shelf Life

As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

Storage

-20ºC Freeze

Form

Powder

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