Description
Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties.
Synonyms
S-7701; S 7701; S7701; AMR69; AMR-69; AMR 69; Pirespa; Pirfenex; Deskar, Esbriet; Etuary
IUPAC Name
5-methyl-1-phenylpyridin-2-one
Molecular Formula
C12H11NO
Canonical SMILES
CC1=CN(C(=O)C=C1)C2=CC=CC=C2
InChI
InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKey
ISWRGOKTTBVCFA-UHFFFAOYSA-N