Pinosylvin

Inquiry

For Research Use Only.

Category

Phenols

Cat.No.

NP4610

CAS

22139-77-1

Product Name

Pinosylvin

Structure

Product Details

Description

Pinosylvin isolated from the herbs of Pinus yunnanensis. Pinosylvin in low concentrations, can promote cell proliferation to endothelial cells and inhibit lipopolysaccharide-induced THP-1 cell adhesion to endothelial cells.

Synonyms

3,5-dihydroxystilbene;

IUPAC Name

5-[(E)-2-phenylethenyl]benzene-1,3-diol

Molecular Weight

212.3

Molecular Formula

C14H12O2

Canonical SMILES

C1=CC=C(C=C1)C=CC2=CC(=CC(=C2)O)O

InChI

1S/C14H12O2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10,15-16H/b7-6+

InChIKey

YCVPRTHEGLPYPB-VOTSOKGWSA-N

Boiling Point

312.08°C (rough estimate)

Melting Point

153-157 °C

Purity

> 95%

Density

1.252g/cm3

Appearance

Powder

Application

antibacterial; antimicrobial; antifungal;

Storage

2-8°C

BRN

1870942

Chemical Properties

Off-white crystalline powder

EINECS

683-184-0

Enzyme Inhibitor

This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. = 155.5-156°C; low solubility in water), also known as (E)-3,5-stilbenediol and trans-3,5-dihydroxystilbene and named systematically as 5-[(E)-2- phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine and other woody plants. Pinosylvin exxhibits micromolar Ki values for specific isozymes of stilbene synthase and chalcone synthase. Target(s): chalcone synthase; stilbene synthase; tyrosinase, or monophenol monooxygenase.

Hazard Class

Xn,N

pKa

9.34±0.10(Predicted)

Refractive Index

1.6000 (estimate)

RIDADR

UN 3077 9 / PGIII

Risk Statements

22-36-51/53

RTECS

WJ5580000

Safety Statements

26-61

Uses

Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility.

WGK Germany

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