Description
Pinoresinol isolated from the bark of Eucommia ulmoides Oliver. It causes an upregulation of the CDK inhibitor p21 both at mRNA and protein levels, owing to Pinoresinol reducing proliferation and induce differentiation on HL60 cells.
Synonyms
(+)-PINORESINOL; (-)-4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol);(3aS,6aS)-3a,4,6,6a-Tetrahydro-3β,6β-bis(4-hydroxy-3-methoxyphenyl)-1H,3H-furo[3,4-c]furan;