Peiminine

Inquiry

For Research Use Only.

Size	Price	Stock	Quantity
25 mg	$199	In stock

Category

Alkaloids

Cat.No.

NP0526

CAS

18059-10-4

Product Name

Peiminine

Structure

Product Details

Description

Peiminine is an alkaloid isolated from Fritillaria. Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. Peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.

Synonyms

Verticinone; Raddeanine

IUPAC Name

(1R,2S,6S,9S,10S,11S,14S,15S,18S,20S,23R,24S)-10,20-dihydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one

Molecular Weight

429.64

Molecular Formula

C27H43NO3

Canonical SMILES

CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)(C)O

InChI

InChI=1S/C27H43NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-23,25,29,31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23+,25-,26+,27-/m0/s1

InChIKey

IQDIERHFZVCNRZ-YUYPDVIUSA-N

Purity

>98%

Appearance

Powder

Application

moistening lung

Color

Orange

Form

Powder