Peimine

Inquiry

For Research Use Only.

Category

Alkaloids

Cat.No.

NP0517

CAS

23496-41-5

Product Name

Peimine

Structure

Product Details

Description

Anti-inflammatory agent. MAPK inhibitor. Inhibits p38, ERK and JNK phosphorylation. Inhibits NFκB activation. Shows antitussive, expectorant and anti-inflammatory effects in vivo. Orally active.

Synonyms

Verticine; Dihydroisoimperialine

IUPAC Name

(1R,2S,6S,9S,10S,11S,14S,15S,17S,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol

Molecular Weight

431.65

Molecular Formula

C27H45NO3

Canonical SMILES

CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O

InChI

InChI=1S/C27H45NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-25,29-31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23+,24-,25-,26+,27-/m0/s1

InChIKey

IUKLSMSEHKDIIP-BZMYINFQSA-N

Purity

>98%

Appearance

Powder

Application

anti-inflammatory

Color

Orange

Form

Powder