Paclitaxel

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For Research Use Only.

Size	Price	Stock	Quantity
2 g	$199	In stock

Category

Diterpenoids

Cat.No.

NP1765

CAS

33069-62-4

Product Name

Paclitaxel

Structure

Product Details

Description

Paclitaxel is a compound with anti-tumor activity extracted from the Pacific yew tree Taxus brevifolia. Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

Synonyms

Docetaxel EP Impurity F; BMS 181339-01; BMS181339-01; BMS-181339-01; Taxol A; Abraxane; Paxene; Taxol

IUPAC Name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Molecular Weight

853.91

Molecular Formula

C47H51NO14

Canonical SMILES

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C

InChI

InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1

InChIKey

RCINICONZNJXQF-MZXODVADSA-N

Boiling Point

957.1°C at 760 mmHg

Melting Point

213-216°C

Flash Point

532.6±34.3 °C

Purity

>98%

Density

1.39 g/cm3

Solubility

DMSO, methanol, ethanol

Appearance

White Solid

Application

ADCs Cytotoxin

Shelf Life

≥360 days if stored properly

Storage

Store at -20°C (dark)

Form

Powder

Packaging

2 g

Toxicity

LD50 = 32530 microg/kg (Rat).

Vapor Pressure

0.0±0.3 mmHg at 25°C

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