p-Phlorizin

Name: PRUNINDIHYDROCHALCONE
Brand: BOC Sciences
Price: 298 USD
Availability: MadeToOrder

Inquiry

For Research Use Only.

Category

Chalcones

Cat.No.

NP0949

CAS

4192-90-9

Product Name

p-Phlorizin

Structure

Product Details

Description

Trilobatin, coming from the herbs of Lithocarpus pachyphyllus, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway. It increased superoxide dismutase (SOD) activity. Besides, Trilobatin is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect.

Synonyms

1-[4-(β-D-Glucopyranosyloxy)-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; p-Phloridzin; Phloretin 4'-glucoside; Phloretin 4'-β-D-glucoside; Phloretin-4-O-glycoside; Phloretin-4'-O-β-D-glucopyranoside; Phloretine-4'-glucoside; Prunin dihydrochalcone; Trilobatin

IUPAC Name

1-[2,6-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one

Molecular Weight

436.41

Molecular Formula

C21H24O10

Canonical SMILES

C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)OC3C(C(C(C(O3)CO)O)O)O)O)O

InChI

InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-12-7-14(25)17(15(26)8-12)13(24)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-23,25-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1

InChIKey

GSTCPEBQYSOEHV-QNDFHXLGSA-N

Boiling Point

787.9±60.0 °C at 760 mmHg

Melting Point

163 °C

Flash Point

277.1±26.4 °C

Purity

>98%

Density

1.6±0.1 g/cm3

Solubility

Soluble in DMF, DMSO, Ethanol

Appearance

White to beige crystalline solid

Application

Anti-inflammatory

Storage

Store at 2-8 °C, protect from light

Form

Powder

HS Code

29329990

pKa

6.85±0.40(Predicted)

Vapor Pressure

0.0±2.9 mmHg at 25°C

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