Description
Oxymatrine is a quinolizidine alkaloid extracted from the root of Sophora flavescens, which is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases. Oxymatrine also can be used in cosmetics material.
Synonyms
Matrine N-oxide; Ammothamnine; Oxysophoridine; Matrine oxide; Matrine 1beta-oxide; Oxymatrine;
IUPAC Name
(1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
Molecular Formula
C15H24N2O2
Canonical SMILES
C1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]
InChI
InChI=1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1
InChIKey
XVPBINOPNYFXID-LHDUFFHYSA-N
Solubility
In vitro:
10 mM in DMSO
Application
anti-hepatitis B virus, anti-inflammation and anti-anaphylaxis.
Storage
Powder:
-20°C: 3 years
4°C: 2 years
In solvent:
-80°C: 6 months
-20°C: 1 month
Vapor Pressure
0mmHg at 25°C