Oridonin

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For Research Use Only.

Size	Price	Stock	Quantity
10 g	$1880	In stock

Category

Diterpenoids

Cat.No.

NP1543

CAS

28957-04-2

Product Name

Oridonin

Structure

Product Details

Description

Oridonin, a diterpenoid purified from Rabdosia rubescens, is an antitumor agent. It also acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.

Synonyms

Rubescenin A; Oridonine; lasidonin; (14R)-7-alpha,20-Epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-one

IUPAC Name

(1S,2S,5S,8R,9S,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one

Molecular Weight

364.43

Molecular Formula

C20H28O6

Canonical SMILES

CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C

InChI

InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1

InChIKey

SDHTXBWLVGWJFT-XKCURVIJSA-N

Boiling Point

599.8±50.0 °C (Predicted)

Melting Point

248-250 °C

Purity

>98%

Density

1.42±0.1 g/cm3 (Predicted)

Appearance

White powder

Application

lipoxygenase-inhibiting

Color

Yellow

Form

Powder

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