Description
Olanzapine interacts with key receptors of interest in schizophrenia, having a nanomolar affinity for dopaminergic, serotonergic, alpha 1-adrenergic, and muscarinic receptors.
Synonyms
LY-170052, LY170052, LY 170052, Olanzapine, Zyprexa, Zolafren
IUPAC Name
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Molecular Weight
312.43975
Molecular Formula
C17H20N4S
Canonical SMILES
CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
InChI
InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
InChIKey
WXPNDRBBWZMPQG-UHFFFAOYSA-N
Solubility
Partly miscible
Appearance
Yellow crystalline solid
Application
Antiemetic, Antipsychotic agent, Serotonin uptake inhibitor