Norfloxacin

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For Research Use Only.

Category

Impurities

Cat.No.

NP3396

CAS

70458-96-7

Product Name

Norfloxacin

Structure

Product Details

Description

Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase. It is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. It is approved for use in children older than one year of age. However, it is associated with a number of rare serious adverse reactions as well as spontaneous tendon ruptures and irreversible peripheral neuropathy.

Synonyms

Noroxin; Chibroxin; AM-715; MK-366; AM 715; MK 366; AM715; MK366; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid; Baccidal; Barazan; Chibroxine; N-Desmethylpefloxacin; Sebercim; Zoroxin

IUPAC Name

1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

Molecular Weight

319.33

Molecular Formula

C16H18FN3O3

Canonical SMILES

CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O

InChI

InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

InChIKey

OGJPXUAPXNRGGI-UHFFFAOYSA-N

Boiling Point

555.8±50.0°C (Predicted)

Melting Point

220-221°C

Purity

>98%

Density

1.344 g/cm3

Solubility

Soluble in Acetone, Chloroform; Freely soluble in Water; Slightly soluble in DMSO, Methanol (Heated)

Appearance

Pale Yellow Solid

Application

Anti-bacterial agents; enzyme inhibitors; nucleic acid synthesis inhibitors

Storage

Store at -20°C under inert atmosphere

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