Nisoldipine

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For Research Use Only.

Category

Impurities

Cat.No.

NP3272

CAS

63675-72-9

Product Name

Nisoldipine

Structure

Description

Nisoldipine is a calcium channel blocker, specific for L-type Cav1.2 with IC50 of 10 nM.

Synonyms

Sulphanilamide

IUPAC Name

3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Molecular Weight

388.41

Molecular Formula

C20H24N2O6

Canonical SMILES

CC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

InChI

InChI=1S/C20H24N2O6/c1-11(2)10-28-20(24)17-13(4)21-12(3)16(19(23)27-5)18(17)14-8-6-7-9-15(14)22(25)26/h6-9,11,18,21H,10H2,1-5H3

InChIKey

VKQFCGNPDRICFG-UHFFFAOYSA-N

Melting Point

138-143 °C

Purity

>98%

Appearance

Yellow crystalline powder

Form

Powder

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