Nefopam hydrochloride

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For Research Use Only.

Category

Impurities

Cat.No.

NP3419

CAS

23327-57-3

Product Name

Nefopam hydrochloride

Structure

Product Details

Description

Nefopam HCl is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.It is widely used, mainly in European countries, for the relief of moderate to severe pain as an alternative to opioid analgesic drugs.

Synonyms

Nefopam Hydrochloride

IUPAC Name

5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride

Molecular Weight

289.8

Molecular Formula

C17H19NO.HCl

Canonical SMILES

CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3.Cl

InChI

InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H

InChIKey

CNNVSINJDJNHQK-UHFFFAOYSA-N

Melting Point

245-250 °C

Purity

>98%

Solubility

>43.5 [ug/mL] (The mean of the results at pH 7.4)

Appearance

White to Off-White Solid

Application

Analgesics, Non-Narcotic

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