Naftifine hydrochloride

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For Research Use Only.

Category

Impurities

Cat.No.

NP3135

CAS

65473-14-5

Product Name

Naftifine hydrochloride

Structure

Product Details

Description

Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.

Synonyms

AW 105843; AW105843; AW-105843; AW 105-843; SN 105843; SN105843; SN-105843; Naftifine hydrochloride

IUPAC Name

(E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine;hydrochloride

Molecular Weight

323.86

Molecular Formula

C21H21N.HCl

Canonical SMILES

CN(CC=CC1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32.Cl

InChI

InChI=1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+;

InChIKey

OLUNPKFOFGZHRT-YGCVIUNWSA-N

Boiling Point

440.1°C at 760 mmHg

Melting Point

172-175°C

Purity

>98%

Solubility

Soluble in DMSO, Methanol

Appearance

White Solid

Storage

Store at -20°C

Form

Powder

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