Moronic acid

For Research Use Only.
Category
Terpenes
Cat.No.
NP6250
CAS
6713-27-5
Product Name
Moronic acid
Structure

Product Details

Description
Moronic acid isolated from the herbs of Rhus chinensis. It shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity.
Synonyms
3-Oxo-5α-olean-18-en-28-oic acid;3-Oxooleana-18-ene-28-oic acid
IUPAC Name
(4aS,6aR,6aR,6bR,8aR,12aR,14aS)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-4,5,6,6a,7,8,8a,11,12,13,14,14a-dodecahydro-3H-picene-4a-carboxylic acid
Molecular Weight
454.7
Molecular Formula
C30H46O3
Canonical SMILES
CC1(CCC2(CCC3(C(C2=C1)CCC4C3(CCC5C4(CCC(=O)C5(C)C)C)C)C)C(=O)O)C
InChI
InChI=1S/C30H46O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h18-19,21-22H,8-17H2,1-7H3,(H,32,33)/t19-,21+,22-,27+,28-,29-,30+/m1/s1
InChIKey
UMYJVVZWBKIXQQ-QALSDZMNSA-N
Melting Point
212 °C(dec.)
Purity
98%
Appearance
Powder
Application
anti-HIV;anti-HSV;anti-EBV
Definition
ChEBI: A pentacyclic triterpenoid that is olean-18-ene substituted at position 3 by an oxo group and position 28 by a carboxy group.
Uses
Moronic Acid and its derivatives can have antidiabetic activity by inhibiting PTP-1B. Moronic Acid is also shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization in rat models.
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