Mizolastine

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For Research Use Only.

Category

Impurities

Cat.No.

NP3543

CAS

108612-45-9

Product Name

Mizolastine

Structure

Product Details

Description

Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.

Synonyms

Mizollen; SL 850324; SL850324; SL-850324; Mistalin; Mistamine; Mizolastina; Mizolastine

IUPAC Name

2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one

Molecular Weight

432.49

Molecular Formula

C24H25FN6O

Canonical SMILES

CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)C5=NC=CC(=O)N5

InChI

InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)

InChIKey

PVLJETXTTWAYEW-UHFFFAOYSA-N

Purity

>98%

Application

Histamine H1 Antagonists, Non-Sedating

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