Description
Miconazole nitrate is an imidazole antifungal agent that blocks ergosterol biosynthesis. It is commonly used as a topical drug for skin infections. It promotes the differentiation of mature oligodendrocytes from progenitor cells.
Synonyms
Albistat; Andergin; Aflorix; 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole nitrate; [2,4-Dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazole Nitrate; Brentan; Conoderm; Conofite; Daktacort; Florid; Fungiderm; Fungisdin; Micatin; Miconal; Zimycan
IUPAC Name
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole;nitric acid
Molecular Formula
C18H15Cl4N3O4
Canonical SMILES
C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-]
InChI
InChI=1S/C18H14Cl4N2O.HNO3/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)
InChIKey
MCCACAIVAXEFAL-UHFFFAOYSA-N
Boiling Point
555.1°C at 760 mmHg
Solubility
Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance
Off-white Solid
Application
14-alpha Demethylase Inhibitors
Storage
Store at -20°C under inert atmosphere