Memantine hydrochloride

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For Research Use Only.

Size	Price	Stock	Quantity
25 g	$299	In stock

Category

Impurities

Cat.No.

NP3138

CAS

41100-52-1

Product Name

Memantine hydrochloride

Structure

Product Details

Description

Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA receptors.It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively.

Synonyms

3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine Hydrochloride; 3,5-Dimethyl-1- adamantanamine; 1-Amino-3,5-dimethyladamantane Hydrochloride; Akatinol; Axura; Ebix; Ebixia; Ebixza; NSC 102290; Namenda; SUN Y7017; Tocris

IUPAC Name

3,5-dimethyladamantan-1-amine;hydrochloride

Molecular Weight

215.76

Molecular Formula

C12H21N.HCl

Canonical SMILES

CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl

InChI

InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H

InChIKey

LDDHMLJTFXJGPI-UHFFFAOYSA-N

Melting Point

>300°C (sublimes)

Purity

>98%

Solubility

29.4 [ug/mL] (The mean of the results at pH 7.4)

Appearance

White crystalline powder

Application

Antiparkinson Agents

Form

Powder

Packaging

25 g

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