Meclizine dihydrochloride

Impurities

NP3687

1104-22-9

Meclizine dihydrochloride

Meclizine dihydrochloride is the salt form of Meclizine, which is a histamine H1 receptor antagonist used to treat motion sickness and dizziness (vertigo). Meclizine has anti-histamine, anti-muscarinic, and anti-oxidative phosphorylation properties.

Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, hydrochloride (1:2); Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-, dihydrochloride; Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, dihydrochloride; 1-((4-Chlorophenyl)(phenyl)methyl)-4-(3-methylbenzyl)piperazine dihydrochloride; 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)piperazine dihydrochloride; Ancolan dihydrochloride; Bonamine; Diadril; Meclizine hydrochloride; Meclozine dihydrochloride; Meclozine hydrochloride; Navidoxine; NSC 28728; Parachloramine dihydrochloride; Postafen; Postafene dihydrochloride; Zentrip

1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;dihydrochloride

463.87

C25H27Cl2N2.2HCl

CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl

InChI=1S/C25H27ClN2.2ClH/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23;;/h2-13,18,25H,14-17,19H2,1H3;2*1H

VCTHNOIYJIXQLV-UHFFFAOYSA-N

204-208°C

>98%

Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)

White to Off-white Solid

Store at -20°C under inert atmosphere