Description
Mebendazole is a benzimidazole anthelmintic and Tubulin-disrupting drug. It has antitumour activity in vitro and in vivo and inhibits growth and induces apoptosis. It is highly effective on various gastrointestinal nematodes in animals, has good effects on some tapeworms, and also effective on Trichinella spiralis. It is used for nematode diseases of horses, sheep, poultry and wild animals, nematodes and tapeworms of dogs and cats.
Synonyms
Vermox; Telmin; Mebenvet; Pantelmin; Vermirax; Ovitelmin; Bantenol; Lomper; MBDZ; Besantin; Noverme; Methyl (5-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate; Sufil; 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester
IUPAC Name
methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate
Molecular Formula
C16H13N3O3
Canonical SMILES
COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3
InChI
InChI=1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)
InChIKey
OPXLLQIJSORQAM-UHFFFAOYSA-N
Boiling Point
436.98°C (Predicted)
Melting Point
>255°C (dec.)
Solubility
Slightly soluble in DMSO (Heated), Methanol (Heated)
Appearance
White to Pale Beige Solid