Description
Matairesinol isolated from the roots of Wikstroemia indica. It could markedly benefit TRAIL-based tumor therapies.
Synonyms
(αR,βR)-α,β-Bis(4-hydroxy-3-methoxybenzyl)butyrolactone;(3R)-3α,4β-Bis(3-methoxy-4-hydroxybenzyl)-4,5-dihydrofuran-2(3H)-one
IUPAC Name
(3R,4R)-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
Molecular Formula
C20H22O6
Canonical SMILES
COc1cc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O)c(OC)c3)ccc1O
InChI
1S/C20H22O6/c1-24-18-9-12(3-5-16(18)21)7-14-11-26-20(23)15(14)8-13-4-6-17(22)19(10-13)25-2/h3-6,9-10,14-15,21-22H,7-8,11H2,1-2H3/t14-,15+/m0/s1
InChIKey
MATGKVZWFZHCLI-LSDHHAIUSA-N
Boiling Point
593.0±45.0 °C(Predicted)
Solubility
Acetone (Slightly), Chloroform (Slightly), methanol (Slightly)
Application
anti-angiogenic activity; anti-osteoporotic activity
Form
White to off-white solid.
pKa
10.02±0.20(Predicted)
Uses
Matairesinol is a principle plant lignan consituent of dietary fiber.