γ-Mangostin

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For Research Use Only.

Size	Price	Stock	Quantity
25 mg	$376	In stock

Category

Xanthones

Cat.No.

NP7258

CAS

31271-07-5

Product Name

γ-Mangostin

Structure

Product Details

Description

gamma-Mangostin isolated from the fruit of Garcinia cambogia is an HIV protease inhibitor. gamma-Mangostin is cytotoxic to HL-60, SMMC-7721, A549, MCF-7, and SW480 cancer cells and BEAS-2B non-cancerous pulmonary epithelial cells in vitro (IC50s = 7.39, 6.57, 10.07, 5.33, 8.4, and 7.43 μM, respectively).

Synonyms

Normangostin

IUPAC Name

1,3,6,7-Tetrahydroxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one

Molecular Weight

396.43

Molecular Formula

C23H24O6

Canonical SMILES

CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)O)CC=C(C)C)O)C

InChI

InChI=1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3

InChIKey

VEZXFTKZUMARDU-UHFFFAOYSA-N

Boiling Point

663.4°C at 760 mmHg

Melting Point

206-208 °C

Purity

98%

Density

1.306 g/cm3

Solubility

methanol: soluble1mg/mL, colorless to yellow

Appearance

Yellow Powder

Application

HIV protease inhibitor

Storage

Store at 2-8°C

Color

Off-white to yellow

Definition

ChEBI: A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense
/ital>, it exhibits antitumour activity.

Form

powder

Hazard Class

pKa

7.05±0.20(Predicted)

Risk Statements

RTECS

ZD6122330

WGK Germany

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