(+)-Magnoflorine

Inquiry

For Research Use Only.

Category

Alkaloids

Cat.No.

NP0015

CAS

2141-09-5

Product Name

(+)-Magnoflorine

Structure

Product Details

Description

Magnoflorine, an natural alkaloid found in coptidis rhizoma, exerts an inhibitory effect against Cu2+-induced lipid peroxidation of high density lipoprotein (HDL), and has beneficial properties on protecting human HDL against lipid peroxidation. Magnoflorine possesses high activity as α-glucosidase inhibitor in vitro and in vivo, which indicates that the compound has antidiabetic potential activity.

Synonyms

4H-Dibenzo[de,g]quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-, (6aS)-; 6aα-Aporphinium, 1,11-dihydroxy-2,10-dimethoxy-6-methyl-; 4H-Dibenzo[de,g]quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-, (S)-; (6aS)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium; Magnoflorine; Thalictrine; Escholine; Thalictrin; Escholin

Molecular Weight

342.4

Molecular Formula

C20H24NO4

Canonical SMILES

OC=1C(OC)=CC=C2C1C=3C(O)=C(OC)C=C4C3C(C2)[N+](C)(C)CC4

InChI

InChI=1S/C20H23NO4/c1-21(2)8-7-12-10-15(25-4)20(23)18-16(12)13(21)9-11-5-6-14(24-3)19(22)17(11)18/h5-6,10,13H,7-9H2,1-4H3,(H-,22,23)/p+1

InChIKey

YLRXAIKMLINXQY-UHFFFAOYSA-O

Melting Point

208 °C

Purity

>98%

Appearance

Brown cryst.

Application

anti-diabetic

Storage

2-8°C(protect from light)

Color

white to light yellow

Form

Powder

MDL

MFCD09031380

NACRES

NA.25

Products

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