Luteolin

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For Research Use Only.

Size	Price	Stock	Quantity
5 g	$199	In stock

Category

Flavonoids

Cat.No.

NP1855

CAS

491-70-3

Product Name

Luteolin

Structure

Product Details

Description

Luteolin is an anti-inflammatory, antioxidant and free radical scavenger. Luteolin inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. It also inhibits TNF-α-induced COX-2 expression, and phosphodiesterase with with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM for PDE1-5 respectively. It inhibits proliferation of Lewis lung carcinoma cells in vivo. Luteolin is a natural compound found in the leaves of Dracocephalum ruyschiana L. It can be used in cosmetics material.

Synonyms

3',4',5,7-Tetrahydroxyflavone; Digitoflavone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; Flacitran

IUPAC Name

2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one

Molecular Weight

286.24

Molecular Formula

C15H10O6

Canonical SMILES

C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O

InChI

InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

InChIKey

IQPNAANSBPBGFQ-UHFFFAOYSA-N

Boiling Point

616-617 °C at 760 mmHg (est)

Melting Point

328-330 °C

Purity

≥98%

Density

1.654 g/cm3

Solubility

Soluble in aqueous alkaline solutions

Appearance

Yellow solid

Application

ADCs Cytotoxin

Storage

In a dry, cool place

Form

Powder

Packaging

5 g

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