Lupenone

For Research Use Only.
Category
Terpenes
Cat.No.
NP6327
CAS
1617-70-5
Product Name
Lupenone
Structure

Product Details

Description
Lupenone is isolated from the roots of Pueraria thomsonii Benth. It effectively inhibited adipocyte differentiation through downregulating the related transcription factor, particularly the PPARγ gene.
Synonyms
18-Lupen-3-one; 5α-Lup-20(29)-en-3-one
IUPAC Name
(1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one
Molecular Weight
424.7
Molecular Formula
C30H48O
Canonical SMILES
CC(=C)C1CCC2(C1C3CCC4C5(CCC(=O)C(C5CCC4(C3(CC2)C)C)(C)C)C)C
InChI
InChI=1S/C30H48O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-23,25H,1,9-18H2,2-8H3/t20-,21+,22-,23+,25+,27+,28-,29+,30+/m0/s1
InChIKey
GRBHNQFQFHLCHO-BHMAJAPKSA-N
Boiling Point
485.7±14.0 °C(Predicted)
Melting Point
165-167°C
Purity
98%
Density
0.973 g/cm3
Solubility
Chloroform (Slightly), methanol (Slightly)
Appearance
White powder
Storage
-20°C Freezer
Color
White
Definition
ChEBI: A natural product found in Cupania cinerea.
Form
Solid
Hazard Class
Xi
HS Code
29142990
Uses
Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor.
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