Description
Lupanine comess from the herbs of Cytisus scoparius. It has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity.
Synonyms
(7aβ,14aα)-Dodecahydro-7α,14α-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one;2-Oxosparteine;d-Lupanine;Lupanin;
IUPAC Name
(1S,2R,9S,10S)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecan-6-one
Molecular Formula
C15H24N2O
Canonical SMILES
C1CCN2CC3CC(C2C1)CN4C3CCCC4=O
InChI
InChI=1S/C15H24N2O/c18-15-6-3-5-14-11-8-12(10-17(14)15)13-4-1-2-7-16(13)9-11/h11-14H,1-10H2/t11-,12-,13-,14+/m0/s1
Application
antimicrobial activity
Alpha
D25 +84° (c = 4.8 in alc)
Definition
ChEBI: The delta-lactam obtained by formal oxidation at the 2-position of sparteine. The major alkaloid from the seeds of Lupinus exaltatus, L. mexicanus and L. rotundiflorus, it is among the most important of the tetracyc
ic quinolizidine alkaloids.
Refractive Index
nD24 1.5444
Uses
(+)-Lupanine is used in biological studies with quinolizidine alkaloids in seeds of lupin genotypes of different origins.