Loureirin A

Chalcones

NP0980

119425-89-7

Loureirin A

Loureirin A is a chalcone extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. It is a part of traditional Chinese medicine which helps combat neurodegenerative diseases. It inhibits platelet activation by an impairment of PI3K/Akt signaling. It also could inhibit Akt phosphorylation. It negatively affects agonist-induced platelet aggregation such as ADP, collagen, thrombin and collagen-related peptide (CRP). It promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound by activating Wnt/-catenin pathway.

3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone

3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one

286.32

C17H18O4

COC1=CC(=C(C=C1)CCC(=O)C2=CC=C(C=C2)O)OC

InChI=1S/C17H18O4/c1-20-15-9-5-13(17(11-15)21-2)6-10-16(19)12-3-7-14(18)8-4-12/h3-5,7-9,11,18H,6,10H2,1-2H3

RSAIVLRELNGZEY-UHFFFAOYSA-N

479.1±40.0 °C at 760 mmHg

98.5%

1.2±0.1 g/cm3

Powder

Powder

250 mg / 500 mg