Losartan

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For Research Use Only.

Category

Impurities

Cat.No.

NP3493

CAS

114798-26-4

Product Name

Losartan

Structure

Product Details

Description

Losartan, an antagonist of angiotensin II receptor, could be effective in the treatment of hypertensive. IC50: 20nM.

Synonyms

Losartan; DUP 89; DUP-89; DUP89; Cozaar; Hyzaar; UNII-JMS50MPO89

Molecular Weight

422.92

Molecular Formula

C22H23ClN6O

Canonical SMILES

CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl

InChI

InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)

InChIKey

PSIFNNKUMBGKDQ-UHFFFAOYSA-N

Boiling Point

682ºC at 760mmHg

Melting Point

183-184ºC

Purity

95%

Density

1.35 g/cm3

Solubility

DMSO 95 mg/mL; Water 95 mg/mL

Appearance

pale yellow solid

Application

Losartan is an antagonist of angiotensin II receptor and could be effective in the treatment of hypertension.

Shelf Life

As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

Storage

-20ºC Freeze

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