Lithocholic acid

For Research Use Only.
Category
Steroids
Cat.No.
NP6107
CAS
434-13-9
Product Name
Lithocholic acid
Structure

Product Details

Description
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.
Synonyms
Lithocholate; 3alpha-Hydroxy-5beta-cholan-24-oic acid; 3alpha-Hydroxycholanic acid; 5beta-Cholanic acid-3alpha-ol
IUPAC Name
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Molecular Weight
376.58
Molecular Formula
C24H40O3
Canonical SMILES
CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
InChI
InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChIKey
SMEROWZSTRWXGI-HVATVPOCSA-N
Boiling Point
511°C at 760mmHg
Melting Point
181-184°C
Flash Point
276.9°C
Purity
>98%
Density
1.073 g/cm³
Solubility
less than 1 mg/mL at 67.5 °F
Appearance
White Solid
Application
Detergents
Shelf Life
1 Year
Storage
Store at -20°C
Form
Powder
Packaging
50 g
Refractive Index
35.5 ° (C=1, EtOH)
RTECS
FZ2275000
Safety Statements
S22-S24/25
Vapor Pressure
1.4E-12mmHg at 25°C
WGK Germany
2
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