Lincomycin

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP2621

CAS

154-21-2

Product Name

Lincomycin

Structure

Product Details

Description

It is produced by the strain of Str. lincolnensis var. lincolnensis NRRL 2936. It's a sugar antibiotic. It has anti-gram-positive bacteria and spirochete effect, and has weak antibacterial effect on some gram-negative bacteria. It can protect mice infected with Staphylococcus aureus, Streptococcus hemolyticus and dicoccus pneumoniae by oral or subcutaneous injection. It also has effect on leptospira in vivo.

Synonyms

(2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; Lincocin; Lincogap; NSC 70731; U 10149a; Clindamycin Phosphate EP Impurity A

IUPAC Name

(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide

Molecular Weight

406.54

Molecular Formula

C18H34N2O6S

Canonical SMILES

CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O

InChI

InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1

InChIKey

OJMMVQQUTAEWLP-KIDUDLJLSA-N

Boiling Point

646.8±55.0°C (Predicted)

Melting Point

148-150°C

Purity

>99% by HPLC

Density

1.29 g/cm3

Solubility

Soluble in Aqueous acid, Methanol, DMSO, Water

Appearance

White Solid

Application

Anti-bacterial agents

Storage

Store at -20°C

Form

Powder

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