Licoflavonol

Flavonoids

NP2399

60197-60-6

Licoflavonol

Licoflavonol is purified from the roots of Glycyrrhiza uralensis. Licoflavonol exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC, thus, it is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs.

3,5,7-trihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one

354.35

C20H18O6

CC(=CCC1=C(C=C2C(=C1O)C(=O)C(=C(O2)C3=CC=C(C=C3)O)O)O)C

InChI=1S/C20H18O6/c1-10(2)3-8-13-14(22)9-15-16(17(13)23)18(24)19(25)20(26-15)11-4-6-12(21)7-5-11/h3-7,9,21-23,25H,8H2,1-2H3

TVMHBSODLWMMMV-UHFFFAOYSA-N

98.0%

Yellow powder

Powder