Licochalcone A

Chalcones

NP0988

58749-22-7

Licochalcone A

Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It is a potent membrane-active agent that transforms normal erythrocytes into echinocytes. It exhibits potent antimalarial activity and might be developed into a new antimalarial drug. It had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy.

4',4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone; 7-Dimethoxycoumarin; 3-Dimethylallyl-4,4'-dihydroxy- 6-methoxychalcon; (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one

338.4

C21H22O4

CC(C)(C=C)C1=C(C=C(C(=C1)C=CC(=O)C2=CC=C(C=C2)O)OC)O

>98%

DMSO,67mg/mL(197.99mM);Ethanol,67mg/mL(197.99mM);Water,<1mg/mL(<1mM)

Yellow powder

2 years if stored properly

3 years -20°Cpowder;6 months-80°Cin solvent

Powder

100 mg