Licochalcone A

For Research Use Only.
Category
Chalcones
Cat.No.
NP0988
CAS
58749-22-7
Product Name
Licochalcone A
Structure

Product Details

Description
Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It is a potent membrane-active agent that transforms normal erythrocytes into echinocytes. It exhibits potent antimalarial activity and might be developed into a new antimalarial drug. It had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy.
Synonyms
4',4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone; 7-Dimethoxycoumarin; 3-Dimethylallyl-4,4'-dihydroxy- 6-methoxychalcon; (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
Molecular Weight
338.4
Molecular Formula
C21H22O4
Canonical SMILES
CC(C)(C=C)C1=C(C=C(C(=C1)C=CC(=O)C2=CC=C(C=C2)O)OC)O
Purity
>98%
Solubility
DMSO,67mg/mL(197.99mM);Ethanol,67mg/mL(197.99mM);Water,<1mg/mL(<1mM)
Appearance
Yellow powder
Shelf Life
2 years if stored properly
Storage
3 years -20°Cpowder;6 months-80°Cin solvent
Form
Powder
Packaging
100 mg
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