Licochalcone A

Name: Licochalcone A
Brand: BOC Sciences
Price: 298 USD
Availability: MadeToOrder

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For Research Use Only.

Category

Chalcones

Cat.No.

NP0988

CAS

58749-22-7

Product Name

Licochalcone A

Structure

Product Details

Description

Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It is a potent membrane-active agent that transforms normal erythrocytes into echinocytes. It exhibits potent antimalarial activity and might be developed into a new antimalarial drug. It had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy.

Synonyms

4,4'-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone; 7-Dimethoxycoumarin; 3-Dimethylallyl-4,4'-dihydroxy-6-methoxychalcone; (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; (2E)-3-[5-(1,1-Dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (E)-

IUPAC Name

(E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

Molecular Weight

338.40

Molecular Formula

C21H22O4

Canonical SMILES

CC(C)(C=C)C1=C(C=C(C(=C1)/C=C/C(=O)C2=CC=C(C=C2)O)OC)O

InChI

InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+

InChIKey

KAZSKMJFUPEHHW-DHZHZOJOSA-N

Boiling Point

532.6±50.0 °C at 760 mmHg

Melting Point

99-100 °C

Purity

>98%

Density

1.171±0.06 g/cm3

Solubility

Soluble in DMF, DMSO, Ethanol, Water

Appearance

Yellow powder

Shelf Life

2 years if stored properly

Storage

Store at -20 °C

Form

Powder

Packaging

100 mg

QC Data

HPLC

HNMR

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