Description
Cereblon binder; induces ubiquitination and degradation of CK1a and transcription factors IKZF1, IKZF3 and SALL4 by E3 ubiquitin ligase
Synonyms
CC5013; CC-5013; CC 5013; IMiD1; Lenalidomide; US brand name: Revlimid
Molecular Formula
C13H13N3O3
Canonical SMILES
NC1=C2CN(C(C2=CC=C1)=O)C3CCC(NC3=O)=O
InChI
GOTYRUGSSMKFNF-UHFFFAOYSA-N
InChIKey
InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
Melting Point
>250°C (dec.)
Solubility
DMSO:25.93mg/mL
Appearance
White solid powder
Shelf Life
>2 years if stored properly
Risk Statements
R36/37/38
Safety Statements
S26; S36
Vapor Pressure
5.2E-15mmHg at 25°C