Leachianone A

For Research Use Only.
Category
Flavonoids
Cat.No.
NP1818
CAS
97938-31-3
Product Name
Leachianone A
Structure

Product Details

Description
Leachianone A isolated from the roots of Sophora flavescens. And it possesses a profound cytotoxic activity against human hepatoma cell line HepG2 in vitro.
Synonyms
leachianone A; 97938-31-3; Isokurarinone; (S)-5,7-Dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-((R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)chroman-4-one; CHEBI:66559; (2S)-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[(2R)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-one; (2S)-5,7,4'-trihydroxy-8-lavandulyl-2'-methoxyflavanone; (2S)-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-2,3-dihydro-4H-chromen-4-one; (2S)-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-3,4-dihydro-2H-1-benzopyran-4-one; leachianoneA; CHEMBL453642; DTXSID801317729; HY-N2281; BDBM50377946; AKOS022185401; MS-27859; CS-0019610; Q27135170
IUPAC Name
(2S)-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[(2R)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-one
Molecular Weight
438.5
Molecular Formula
C26H30O6
Canonical SMILES
CC(=CCC(CC1=C2C(=C(C=C1O)O)C(=O)CC(O2)C3=C(C=C(C=C3)O)OC)C(=C)C)C
InChI
InChI=1S/C26H30O6/c1-14(2)6-7-16(15(3)4)10-19-20(28)12-21(29)25-22(30)13-24(32-26(19)25)18-9-8-17(27)11-23(18)31-5/h6,8-9,11-12,16,24,27-29H,3,7,10,13H2,1-2,4-5H3/t16-,24+/m1/s1
InChIKey
YLTPWCZXKJSORQ-GYCJOSAFSA-N
Boiling Point
649.7±55.0°C at 760 mmHg
Purity
≥95%
Density
1.215±0.06 g/cm3
Solubility
Soluble in Acetone, Chloroform, Dichloromethane, DMSO, Ethyl Acetate
Appearance
Powder
Storage
Store at 2-8°C
Form
Powder
pKa
7.67±0.40(Predicted)
Uses
Leachianone A is a phenolic compound isolated from sophora flavescens soland with potential anti-malarial and anti-inflammatory properties.
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