Description
It is produced from the Aspergillus parasiticus. Kojic Acid has anti-leptospira effect with MIC of 1-10 μg/mL. It is also a tyrosinase inhibitor, which acts as a chelating agent that inhibits the production of melanin and should help chloasma in vitro.
Synonyms
5-Hydroxy-2-(hydroxymethyl)-4-pyrone; 4H-PYRAN-4-ONE, 5-HYDROXY-2-(HYDROXYMETHYL)-; 2-Hydroxymethyl-5-hydroxy-gamma-pyrone; NSC 1942
IUPAC Name
5-hydroxy-2-(hydroxymethyl)pyran-4-one
Canonical SMILES
C1=C(OC=C(C1=O)O)CO
InChI
InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
InChIKey
BEJNERDRQOWKJM-UHFFFAOYSA-N
Boiling Point
401.67°C at 760 mmHg
Melting Point
152-155°C (lit.)
Solubility
Soluble in water, acetone (freely soluble), ethanol (freely soluble), methanol, DMSO, ethyl acetate (slightly soluble), chloroform (slightly soluble), pydidine (slightly soluble), and ether (slightly soluble). Insoluble in benzene.
Appearance
Colorless Acicular Crystalline
Stability
Stable. Combustible. Incompatible with strong oxidizing agents.