Kaurenoic acid

For Research Use Only.
Category
Diterpenoids
Cat.No.
NP1523
CAS
6730-83-2
Product Name
Kaurenoic acid
Structure

Product Details

Description
Kaurenoic acid is a natural diterpenoid found in the herbs of Croton antisyphiliticus. Kaurenoic acid has anti-inflammatory activity, and also exhibits cytotoxic and embryotoxic effects. It acts through inhibition of iNOS and COX-2 expression.
Synonyms
(-)-Kaur-16-en-18-oic acid;Cunabic acid;Kaurane-16-ene-18-oic acid;ent-Kaur-16(17)-en-19-oic acid;ent-Kaur-16-en-19-oic acid;NSC 339145;Kaur-16-en-18-oic acid,(4a)-
Molecular Weight
302.46
Molecular Formula
C20H30O2
Boiling Point
426.6±34.0 °C(Predicted)
Melting Point
171-172 °C
Purity
>98%
Density
1.10±0.1 g/cm3(Predicted)
Appearance
Powder
Application
anti-inflammatory
Storage
Sealed in dry,Store in freezer, under -20°C
Color
Yellow
Definition
ChEBI: An ent-kaurane diterpenoid that is ent-kauran-19-oic acid in which a double bond is present at position 16(17); exhibits anticancer and anti-HIV 1 activity.
Form
Powder
Packaging
25 mg / 100 mg
pKa
4.70±0.40(Predicted)
Uses
ent-Kaurenoic Acid can be used in biological study. Kinetic profile of guaco syrup metabolites like coumarin, 7-hydroxycoumarin, o-coumaric acid, kaurenoic acid can be performed for identification of alternative route of coumarin metabolism in human plasma.
WGK Germany
3
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