Description
Jolkinolide A is extracted from the herbs of Stellera chamaejasme Linn. It belongs to a kind of diterpenoid.
Synonyms
(1aS,3aR,7aS,7bS,11bR)-4,4,7a,11-tetramethyl-3,3a,4,5,6,7,7a,7b-octahydro-2H-oxireno[2',3':1,10a]phenanthro[3,2-b]furan-10(11bH)-one; (4aR,6aS,7aβ)-2,3,4,4aα,5,6,11aα,11b-Octahydro-4,4,8,11bβ-tetramethyl-1H-oxireno[1,10a]phenanthro[3,2-b]furan-9(7aH)-one; (5β,9β,10α)-8β,14β:12,16-Diepoxyabieta-11,13(15)-dien-16-one
IUPAC Name
(1S,3R,10S,11R,16R)-5,11,15,15-tetramethyl-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadeca-4,8-dien-6-one
Molecular Formula
C20H26O3
Canonical SMILES
CC1=C2C3C4(O3)CCC5C(CCCC5(C4C=C2OC1=O)C)(C)C
InChI
InChI=1S/C20H26O3/c1-11-15-12(22-17(11)21)10-14-19(4)8-5-7-18(2,3)13(19)6-9-20(14)16(15)23-20/h10,13-14,16H,5-9H2,1-4H3/t13-,14+,16-,19-,20+/m1/s1
InChIKey
OYXDHOVYZKWSRM-PHJMNMFVSA-N
Boiling Point
479.5±45.0 °C(Predicted)
Density
1.19±0.1 g/cm3(Predicted)
Definition
ChEBI: A natural product found in Euphorbia fischeriana.
Uses
Jolkinolide A can be used as a bone marrow mesenchymal stem cell osteogenic differentiation accelerator. It can be developed using matrix solid-phase dispersion coupled with high-performance liquid chromatography.