Jatrorrhizine

Inquiry

For Research Use Only.

Category

Alkaloids

Cat.No.

NP0829

CAS

3621-38-3

Product Name

Jatrorrhizine

Structure

Product Details

Description

Jatrorrhizine, coming from the barks of Phellodendron chinense Schneid, was a safe and potential antihypercholesterolemic agent from RC which could improve the utilization and excretion of cholesterol by up-regulating the mRNA and protein expression of LDLR and CYP7A1. It increases contractility of gastric antral and ileum smooth muscles of rat gastrointestinal tract. Jatrorrhizine offset postoperative ileus-induced delayed gastric emptying and intestinal transit in rats, an action mediated via the cholinergic pathway, but not involving activation of 5-HT(4) receptors.

Synonyms

NEPROTINE HCL; NEPROTINE IODIDE; YATROIZINE HCL; YATROIZINE IODIDE; JATRORRHIZINE CHLORIDE; JATRORRHIZINE HCL; JATRORRHIZINE IODIDE; jatrorrhizine

Molecular Weight

338.4

Molecular Formula

C20H20NO4

Purity

>98%

Appearance

Yellow powder

Application

Antihypercholesterolemic