Jatrorrhizine

For Research Use Only.
Category
Alkaloids
Cat.No.
NP0829
CAS
3621-38-3
Product Name
Jatrorrhizine
Structure

Product Details

Description
Jatrorrhizine, coming from the barks of Phellodendron chinense Schneid, was a safe and potential antihypercholesterolemic agent from RC which could improve the utilization and excretion of cholesterol by up-regulating the mRNA and protein expression of LDLR and CYP7A1. It increases contractility of gastric antral and ileum smooth muscles of rat gastrointestinal tract. Jatrorrhizine offset postoperative ileus-induced delayed gastric emptying and intestinal transit in rats, an action mediated via the cholinergic pathway, but not involving activation of 5-HT(4) receptors.
Synonyms
NEPROTINE HCL; NEPROTINE IODIDE; YATROIZINE HCL; YATROIZINE IODIDE; JATRORRHIZINE CHLORIDE; JATRORRHIZINE HCL; JATRORRHIZINE IODIDE; jatrorrhizine
Molecular Weight
338.4
Molecular Formula
C20H20NO4
Purity
>98%
Appearance
Yellow powder
Application
Antihypercholesterolemic
Form
Powder
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