Isolupalbigenin

Flavonoids

NP2262

162616-70-8

Isolupalbigenin

Isolupalbigenin is extracted from the leaves of Cudrania tricuspidata. It inhibits human glyoxalase I in vitro. It displays promising cytotoxic effects toward HL-60 cells with IC50 value rang from 4.3 ± 0.7 to 18.0 ± 1.7 uM. It has two different antibacterial activities against MRSA including intensifing methicillin sensitivity and inhibiting growth directly. It may be useful for new approaches development against MRSA infection.

3',8-Di-(dimethylallyl)-genistein; 5,7-Dihydroxy-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8-(3-methylbut-2-enyl)chromen-4-one

5,7-dihydroxy-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8-(3-methylbut-2-enyl)chromen-4-one

406.48

C25H26O5

CC(=CCC1=C(C=CC(=C1)C2=COC3=C(C2=O)C(=CC(=C3CC=C(C)C)O)O)O)C

InChI=1S/C25H26O5/c1-14(2)5-7-17-11-16(8-10-20(17)26)19-13-30-25-18(9-6-15(3)4)21(27)12-22(28)23(25)24(19)29/h5-6,8,10-13,26-28H,7,9H2,1-4H3

FXJPTJQFJYNFKC-UHFFFAOYSA-N

97.5%

Yellow powder

Powder