Isoliquiritigenin

For Research Use Only.
Category
Chalcones
Cat.No.
NP0979
CAS
961-29-5
Product Name
Isoliquiritigenin
Structure

Product Details

Description
Isoliquiritigenin, a flavonoid from the root of Glycyrrhiza glabrat, inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μm. It has antioxidant, anti-inflammatory, and anti-tumor activities.
Synonyms
(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; GU 17; 6'-deoxychalcone; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-; trans-2',4,4'-trihydroxychalcone
IUPAC Name
(E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
Molecular Weight
256.25
Molecular Formula
C15H12O4
Canonical SMILES
C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O
InChI
InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
InChIKey
DXDRHHKMWQZJHT-FPYGCLRLSA-N
Boiling Point
504.0±42.0°C (Predicted)
Melting Point
>193°C (dec.)
Flash Point
272.7±24.4 °C
Purity
>98%
Density
1.384±0.06 g/cm3 (Predicted)
Solubility
Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Appearance
Yellow powder
Application
antidiabetic; antitumour; antioxidant; anti-inflammatory; antimutagenic; antifungal;
Storage
Store at 2-8°C
Form
Powder
MDL
MFCD00075907
Packaging
5 g
Vapor Pressure
0.0±1.3 mmHg at 25°C

QC Data

  • Verification code
Online Inquiry
  • Verification code
×
Top
Inquiry Basket