Isoliquiritigenin

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For Research Use Only.

Size	Price	Stock	Quantity
5 g	$519	In stock

Category

Chalcones

Cat.No.

NP0979

CAS

961-29-5

Product Name

Isoliquiritigenin

Structure

Product Details

Description

Isoliquiritigenin, a flavonoid from the root of Glycyrrhiza glabrat, inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μm. It has antioxidant, anti-inflammatory, and anti-tumor activities.

Synonyms

(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; GU 17; 6'-deoxychalcone; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-; trans-2',4,4'-trihydroxychalcone

IUPAC Name

(E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one

Molecular Weight

256.25

Molecular Formula

C15H12O4

Canonical SMILES

C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O

InChI

InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+

InChIKey

DXDRHHKMWQZJHT-FPYGCLRLSA-N

Boiling Point

504.0±42.0°C (Predicted)

Melting Point

>193°C (dec.)

Flash Point

272.7±24.4 °C

Purity

>98%

Density

1.384±0.06 g/cm3 (Predicted)

Solubility

Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Appearance

Yellow powder

Application

antidiabetic; antitumour; antioxidant; anti-inflammatory; antimutagenic; antifungal;

Storage

Store at 2-8°C

Form

Powder

MDL

MFCD00075907

Packaging

5 g

Vapor Pressure

0.0±1.3 mmHg at 25°C

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