Irisflorentin

For Research Use Only.
Category
Flavonoids
Cat.No.
NP2531
CAS
41743-73-1
Product Name
Irisflorentin
Structure

Product Details

Description
Irisflorentin, which can be found in the rhizomes of Belamcanda chinensis (L.) DC, may exert its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression to block apoptosis pathways. These findings encourage further investigation on Irisflorentin as a possible potent agent for PD treatment. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Furthermore, it also significantly inhibits TNF-α, IL-1β and IL-6 at both the transcriptional and translational levels.
Synonyms
IRISFLORENTIN; 3',4',5,5'-Tetramethoxy-6,7-(epoxymethanoxy)isoflavone; 7-(3,4,5-Trimethoxyphenyl)-9-methoxy-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one
IUPAC Name
9-methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one
Molecular Weight
386.35
Molecular Formula
C20H18O8
Canonical SMILES
COC1=CC(=CC(=C1OC)OC)C2=COC3=CC4=C(C(=C3C2=O)OC)OCO4
InChI
InChI=1S/C20H18O8/c1-22-13-5-10(6-14(23-2)18(13)24-3)11-8-26-12-7-15-19(28-9-27-15)20(25-4)16(12)17(11)21/h5-8H,9H2,1-4H3
InChIKey
RISXUTCDCPHJFQ-UHFFFAOYSA-N
Purity
>98%
Appearance
Yellow powder
Application
Anti-inflammatory
Form
Powder
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