Irisflorentin

Inquiry

For Research Use Only.

Category

Flavonoids

Cat.No.

NP2531

CAS

41743-73-1

Product Name

Irisflorentin

Structure

Product Details

Description

Irisflorentin, which can be found in the rhizomes of Belamcanda chinensis (L.) DC, may exert its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression to block apoptosis pathways. These findings encourage further investigation on Irisflorentin as a possible potent agent for PD treatment. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Furthermore, it also significantly inhibits TNF-α, IL-1β and IL-6 at both the transcriptional and translational levels.

Synonyms

IRISFLORENTIN; 3',4',5,5'-Tetramethoxy-6,7-(epoxymethanoxy)isoflavone; 7-(3,4,5-Trimethoxyphenyl)-9-methoxy-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one

IUPAC Name

9-methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one

Molecular Weight

386.35

Molecular Formula

C20H18O8

Canonical SMILES

COC1=CC(=CC(=C1OC)OC)C2=COC3=CC4=C(C(=C3C2=O)OC)OCO4

InChI

InChI=1S/C20H18O8/c1-22-13-5-10(6-14(23-2)18(13)24-3)11-8-26-12-7-15-19(28-9-27-15)20(25-4)16(12)17(11)21/h5-8H,9H2,1-4H3

InChIKey

RISXUTCDCPHJFQ-UHFFFAOYSA-N