Irisflorentin

Flavonoids

NP2531

41743-73-1

Irisflorentin

Irisflorentin, which can be found in the rhizomes of Belamcanda chinensis (L.) DC, may exert its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression to block apoptosis pathways. These findings encourage further investigation on Irisflorentin as a possible potent agent for PD treatment. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Furthermore, it also significantly inhibits TNF-α, IL-1β and IL-6 at both the transcriptional and translational levels.

IRISFLORENTIN; 3',4',5,5'-Tetramethoxy-6,7-(epoxymethanoxy)isoflavone; 7-(3,4,5-Trimethoxyphenyl)-9-methoxy-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one

9-methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one

386.35

C20H18O8

COC1=CC(=CC(=C1OC)OC)C2=COC3=CC4=C(C(=C3C2=O)OC)OCO4

InChI=1S/C20H18O8/c1-22-13-5-10(6-14(23-2)18(13)24-3)11-8-26-12-7-15-19(28-9-27-15)20(25-4)16(12)17(11)21/h5-8H,9H2,1-4H3

RISXUTCDCPHJFQ-UHFFFAOYSA-N

>98%

Yellow powder

Anti-inflammatory

Powder