Description
Irigenin is a natural compound isolated from the rhizomes of Belamcanda chinensis (L.) DC. Irigenin prevents metastatic capacity of lung cancer cells by selectively blocking Extra Domain A. Irigenin has anti-inflammatory effects that can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable cytotoxic effect.
Synonyms
5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one
IUPAC Name
5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one
Molecular Formula
C18H16O8
Canonical SMILES
COC1=CC(=CC(=C1OC)O)C2=COC3=CC(=C(C(=C3C2=O)O)OC)O
InChI
InChI=1S/C18H16O8/c1-23-13-5-8(4-10(19)17(13)24-2)9-7-26-12-6-11(20)18(25-3)16(22)14(12)15(9)21/h4-7,19-20,22H,1-3H3
InChIKey
TUGWPJJTQNLKCL-UHFFFAOYSA-N
Boiling Point
646.1°C at 760 mmHg