Indirubin

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For Research Use Only.
Category
Alkaloids
Cat.No.
NP0564
CAS
479-41-4
Product Name
Indirubin
Structure

Product Details

Description
Indirubin is an inhibitor of GSK-3β and cyclin-dependent kinases (CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p35). Also, Indirubin is a specific Aryl Hydrocarbon receptor (AHR) ligand.
Synonyms
Indirubin; C.I. 73200, Couroupitine B, Indigo red, Indigopurpurin, NSC 105327; NSC-105327; NSC105327; Indigopurpurin; Couroupitine B; [2,3'-Biindolinylidene]-2',3-dione; 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one
IUPAC Name
2-(2-hydroxy-1H-indol-3-yl)indol-3-one
Molecular Weight
262.268
Molecular Formula
C16H10N2O2
Canonical SMILES
C1=CC=C2C(=C1)C(=C(N2)O)C3=NC4=CC=CC=C4C3=O
InChI
InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,18,20H
InChIKey
JNLNPCNGMHKCKO-UHFFFAOYSA-N
Boiling Point
496.6±45.0 °C at 760 mmHg
Purity
>98%
Density
1.4±0.1 g/cm3
Appearance
Dark Red Solid
Application
Antibiotics, Antineoplastic
Storage
Store at -20°C
Form
Powder
Packaging
200 mg
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