Description
Imperatorin isolated from the root of Angelica dahurica Benth. et Hook. It can suppress multidrug-resistant human liver cancer growth in vivo by inducing Mcl-1 degradation. Imperatorin can be used in health products.
Synonyms
9-[(3-Methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one; Imperatorin; Pentosalen; Ammidin; Marmelosin
IUPAC Name
9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
Molecular Formula
C16H14O4
Canonical SMILES
O=C1C=CC2=CC3=C(OC=C3)C(OC/C=C(C)/C)=C2O1
InChI
1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3
InChIKey
OLOOJGVNMBJLLR-UHFFFAOYSA-N
Solubility
Slightly soluble in water
Application
anti-HIV; anticonvulsant; anti-inflammatory; antimicrobial;